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Wednesday, July 31, 2019

Yoga in Regulated Lipid Metabolism

Yoga therapy may have a profound effect in improved lipid metabolism, thus reducing the risk of early onset of dyslipidemia, some studies suggested.

Lipid metabolism is a natural process of our body in break down or storage of fats for energy after consumed food.


Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In a self-as-control study of 36 male healthy volunteers between the age group of 30-58 years assigned to yoga therapy with a validated questionnaire and divided into Vata-Pitta (n = 16) and Pitta-Kapha (n = 20) groups, researchers indicated that

1. Group with Vata-Pitta (V-P) displayed a significant decrease in the levels of TC, LDL (p < 0.001) and significant increase in HDL (p < 0.01) in compared to While, Pitta-Kapha (P-K) group with significant decrease in TC (p < 0.001), TG (p < 0.01), LDL (p < 0.001) and VLDL (p < 0.05) levels.
2. In compared to the P-K group, the levels of baseline levels of TC, TG and VLDL were lower in V-P group

The result showed that both yoga intervention have had a positive effect on promoted lipid metabolism but lesser in the Pitta-Kapha group.

Dr. Doddoli S, the led author said, "yoga practices can effectively regulate lipid metabolism and total body energy expenditure with reference to specific constitutional type".


Additionally, in a prospective, randomized, interventional controlled trial recruited 90 adolescents aged between 15 and 18 years met the Rotterdam criteria for PCOS assigned to yoga group practiced Surya namaskar, asanas, pranayama, and meditation 1 hour per day each day for 12 weeks and group practiced conventional physical exercises acted as control, after taking into account of other confounders, researchers suggested
1. Both groups reported a significant effect on fasting insulin, fasting blood glucose, but significantly different in homeostasis model assessment of insulin resistance.
2. Yoga group expressed a positive effect in all aspects of lipid metabolism


Further analysis, researchers insisted, "(Yoga is) more effective than conventional physical exercises in improving glucose, lipid, and insulin values, including insulin resistance values, in adolescent girls with PCOS independent of anthropometric changes".

More importantly, in the investigation of yoga therapy in reduced risk lipid peroxidation, scientists postulated that yoga practice decreased oxidative stress through the expression of lower concentration of thiobarbituric acid reactive substances, involving autoxidative alterations of fats and oils.


Taking all together, yoga not only have a profound effect in reduce levels of bad cholesterol but also improved lipid metabolism in reduced overexpression of lipid peroxidation.

For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of yoga training on lipid metabolism in industrial workers with reference to body constitution (Prakriti) by Doddoli S1, Shete S1, Kulkarni D1, Bhogal R1.(PubMed)
(2) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome by Nidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)
(2) Effect of a comprehensive yoga-based lifestyle modification program on lipid peroxidation by Yadav RK1, Ray RB, Vempati R, Bijlani RL.(PubMed)

Phytochemical Betacyanins, the Best Chemo-Drugs Enhancer

Chemo-drugs are a class of conventional medicine used for the treatment of cancers. including 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate.

Compared to other treatments, chemotherapy targets cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.

Chemo drugs have been found to improve the survival rate of cancer patients. However, they also induce significant side effects.

Most common side effects of chemo-drugs are fatigue, hair loss, easy bruising, and bleeding. infection, anemia (low red blood cell counts) nausea and vomiting, appetite changes and constipation.

The side effects of chemo drugs are the results of damage to the healthy blood-forming cells in the bone marrow, hair follicles, and cells in the mouth, digestive tract, and reproductive system.

According to the American Cancer Society, some chemo drugs have also been found to damage cells in the heart, kidneys, bladder, lungs, and nervous system.

Therefore, for patients who are at a higher risk of severe symptoms, medicines are taken with the chemo. Sometimes they are the must to help protect your body’s normal cells.

Conventionally, most chemo drugs side effects go away fairly quickly, but some may take months or even years for the symptoms to go away completely.

However, chemo-drugs that cause long-term damage to the heart, lungs, kidneys, or reproductive organs are irreversible.

Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belongings to the group of betalains, found abundantly in beets, chard, etc.

With an aim to find a chemical compound that enhances the chemo drug efficacy and reduces the chemotoxicity, researchers examined the extract of red beetroot (Beta vulgaris L.), the FDA approved red food color E162, in the development of multi-organ tumors in experimental animals.

By comparing the cytotoxic effect of the red beetroot extract with an anti-cancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3) and in the well-established estrogen receptor-positive human breast cancer cells (MCF-7), researchers found that
* Both doxorubicin and the beetroot extract exhibited a dose-dependent cytotoxic effect in both PC-3 and MCF-7cancer cell lines.

* Doxorubicin, at the concentration of 29 µg/m., completely inhibited the growth of the PC-3 cells in three days.

* Although the cytotoxicity of the beetroot extract was significantly lower compared to doxorubicin, the extract continued to decrease the growth rate of the PC-3 cells (3.7% in 3 days vs. 12.5% in 7 days) at the same concentration.


In other words, both beetroot extract and Doxorubicin exerted a significant cytotoxic activity against the tested cancer cell line. However, the efficacy of beetroot extract is lower compared to those of Doxorubicin.

According to the chemical analysis, betacyanin was found to play an important role in the cytotoxicity exhibited by the red beetroot extract.


Moreover, betaxanthins and betacyanins used in combination with conventional anticancer drugs were found to reduce the chemo drug toxicity and overcome the multidrug resistance of cancer cells.

Based on the finding, researchers concluded betacyanins used alone or combined with other phytochemicals or chemo drug to block the onset of the proliferation of tumor cells.


Taken altogether, betacyanins found in beetroot extract used alone or combined with conventional anti-cancer medicine to enhance the chemo-drugs efficacy and reduce chemotoxicity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of betacyanins in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(2) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES. (PubMed)

Tuesday, July 30, 2019

Yoga Induced Calmness Under Great Pressure

Yoga may be one of the best practice to induce calmness for people who are at the state of constant pressure, some studies suggested

Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study of 13 normal healthy adults to determine the effects of alternate nostril yoga breathing on (a) cerebral hemisphere asymmetry, and (b) changes in the standard EEG bands by assigned the participants into three sessions (a) alternate nostril yoga breathing (ANYB), (b) breath awareness and (c) quiet sitting, on separate days, researchers showed that alternate nostril yoga breathing (ANYB) expressed a higher result in induced calmness through stress and anxiety reduction.


Yoga alternate nostril breathing exercise demonstrated a significant effect to individuals calmness under certain pressure, probably is a result in the settle the mind and body, and emotions and decreased expression of an overactive or worrying mind.

Interestingly, certain posts in the sequence culminating in Padmasana(Lotus Pose) have found to achieve a calm mind stage, according to yoga journal.
Other researchers suggested that yoga inner demonstration of calmness may also have a profound effect in the healing process of the whole person--mind, body, and spirit.


Dr. Ott MJ at the Dana Farber Cancer Institute, said, "Formal and informal daily practice fosters the development of profound inner calmness and nonreactivity of the mind, allowing individuals to face, and even embrace, all aspects of daily life, regardless of circumstances".


Indeed, yoga found the inner peace of participants through intimacy and ability to listen to the body even in sadness, grief and other festering emotions.

More importantly, in a study of 8 healthy male volunteers of the age group 25.9 +/- 3 (SD) years assigned to Santhi Kriya practice daily for 50 minutes for 30 days with volunteer's body weight, blood pressure, oral temperature, pulse rate, respiration, ECG and EEG were recorded before and after the practice on the 1st day and subsequently on 10th, 20th and 30th day of their practice, researchers at the end of the experiment postulated that there was a gradual and significant decrease in the body weight and an increase in alpha activity of the brain (P less than 0.001) during the course of 30 days.

Further analysis also suggested that the increase of alpha activity both in occipital and prefrontal areas of both the hemispheres of the brain indicated an increase of calmness.


More importantly, Santhi Kriya practice expressed an increases oral temperature by 3 degrees F and decreases respiratory rate significantly on all practice days.


Santhi Kriya yoga, a mixture of combined yogic practices of breathing and relaxation.

According to Dr. Richard P. Brown, Patricia L. Gerbarg, Philip R. Muskin in the book of
How to Use Herbs, Nutrients, & Yoga in Mental Health, Santhi Kriya total cortical alpha activity in the brain is associated to relaxation calmness and awareness and the practice may be considered as an adjunct therapy to induce a state of greater relaxation.


Taking all together, there is no doubt that people engaged in yoga lessons regularly are less likely to make the wrong decision under pressure because of the result of yoga in the expression of greater calmness.


For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Hemisphere specific EEG related to alternate nostril yoga breathing by Telles S1, Gupta RK2, Yadav A2, Pathak S2, Balkrishna A2.(PubMed)
(2) Yoga breathing through a particular nostril is associated with contralateral event-related potential changes by Telles S1, Joshi M, Somvanshi P.(PubMed)
(3) Effect of Santhi Kriya on certain psychophysiological parameters: a preliminary study by Satyanarayana M1, Rajeswari KR, Rani NJ, Krishna CS, Rao PV.(PubMed)

Herbal Turmeric Reduces the Risk of Diabetic Nephropathy in Diabetes, According to Researchers

Diabetic nephropathy (diabetic kidney disease) is a complication of kidney damage caused by diabetes.

Long-term unmanaged hyperglycemia can damage the part of the kidneys thus reducing the kidney function in filter waste from the blood filters, leading to 'leaky' syndrome that allows protein into your urine.

Diabetic nephropathy is the 3 stage of kidney change in patients with diabetes. In this stage, patients may experience symptoms of abnormally elevated urinary albumin excretion, compared to the 15 and 300 μg/min in the baseline situation.


The progression of diabetic nephropathy that leads to an increased rate in albumin excretion is higher in patients with increased blood pressure.

More importantly, if high blood pressure is left untreated, diabetic nephropathy can induce persistent proteinuria >0.5 g/ 24 h that furtherly decline the renal function with the mean fall rate being around 1 ml/min/mo.

In other words, by treating hypertension and hyperglycemia in patients with diabetes, the progression of diabetics kidney disease may be slowed or preventable.

Some researchers suggested that
* By maintaining a healthy blood glucose levels and keeping them within the target range.

* By a change of healthful diet.

* By getting moderate and regular exercise

* By maintaining a healthy weight

* Particularly, by following a treatment plan, including the use of insulin or other medications.

Most common symptoms of diabetic nephropathy are worsening blood pressure control, protein in the urine, swelling of feet, ankles, hands or eyes, frequent urination, confusion or difficulty concentrating.

If you are diabetes associated with the aforementioned symptoms, please check with your doctor to rule out the possibility.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a potential and natural source for the treatment of diabetic complications, researchers examined the effects of bioactive compound curcumin anti-diabetic nephropathy (DN), the most common cause of end-stage renal disease in most parts of the world.

40 patients in the Diabetes Clinic of the Outpatient Department of Shiraz University of Medical Sciences on with overt type 2 diabetic nephropathy were randomized into a trial group (n = 20) and a control group (n = 20).

The treatment group received one capsule with each meal containing 500 mg turmeric, of which 22.1 mg was the active ingredient curcumin (three capsules daily) compared to the control group received three capsules identical in color and size containing starch for the period of 2 months.

Compared to the control group. patients treated with turmeric showed significantly reduced serum levels of transforming growth factor-β (TGF-β) and IL-8 associated with the production of pro-inflammatory cytokine and urinary protein excretion, the indications of kidney dysfunction.

The same results were also found in the comparison of the pre- and post-turmeric supplementation values.

Furthermore, there is no side effect reported in patients of the treatment group.


In other words, turmeric containing curcumin used in the experiment protects the kidney cells against the onset of diabetic nephropathy without inducing any adverse effects.

Dr. Khajehdehi P, the lead scientist based on the finding wrote, "Short-term turmeric supplementation can attenuate proteinuria, TGF-β, and IL-8 in patients with overt type 2 diabetic nephropathy and can be administered as safe adjuvant therapy for these patients".


Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of diabetic nephropathy, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of curcumin in experimental diabetic nephropathy by Prabhakar SS. (PubMed)
(2) Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: a randomized, double-blind and placebo-controlled study by Khajehdehi P1, Pakfetrat M, Javidnia K, Azad F, Malekmakan L, Nasab MH, Dehghanzadeh G. (PubMed)
(3) The Stages in Diabetic Renal Disease: With Emphasis on the Stage of Incipient Diabetic Nephropathy by C E Mogensen, C K Christensen and E Vittinghus(The Diabetes Association)

Monday, July 29, 2019

Yoga and Your Heart

Yoga may have a profound effect in improved heart rate regardless of patients precondition, some institution studies suggested


Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study to examine the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women (n=52) randomly assigned to a yoga(comprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation) group or a control group, in compared to control, yoga group expressed insignificant change in heart rate.

But after taking into account of other confounders, researchers insisted that long term yoga lessons may have a positive effect in heart rate in women with higher levels of stress and trait anxiety.


Other researchers in the concern of the effect of yoga in reduced high blood pressure but not heart rate launched an investigation of 26 male volunteers assigned either in yoga with assessment taken at 3-time points: Pre (5 minutes), during (15 minutes; for ANYB or BAW) and Post (5 minutes)
1. Yoga group expressed a significant decrease (repeated measures ANOVA) in systolic BP and respiration rate
2. Breath rate was found to be the difference in all 3 intervals, measured by awareness (BAW) assay.

Further assessment, Dr. Telles S, the led author suggested that the vagal activity involved in heart rate regulation increased during and after ANYB, may contribute to the decrease in BP and changes in the HRV.

More importantly, in randomized clinical trials (RCTs) in compared yoga against any type of control intervention in healthy individuals or patients with any medical condition, through searching the literature published online database wit 14 studies satisfied the criteria selected, researchers found that
1. Yoga intervention expressed in Ten RCTs showed favorable effects of yoga on various domains of HRV,
2. The meta-analysis (MA) of two trials did not show the favourable effects of yoga compared to usual care.

After taking into account other influences, researchers suggested that there was no convincing evidence for the effectiveness of yoga in modulating HRV in patients or healthy subjects.


The finding, although showed contradictory results of yoga in improved heart rate, some researchers insisted that long term intervention may prove the differences

For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Yoga on Heart Rate Variability and Mood in Women: A Randomized Controlled Trial by Chu IH1, Lin YJ1, Wu WL1, Chang YK2, Lin IM3.(PubMed)
(2) Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness by Telles S1, Sharma SK1, Balkrishna A1.(PubMed)
(3) Yoga for Heart Rate Variability: A Systematic Review and Meta-analysis of Randomized Clinical Trials.by Posadzki P1, Kuzdzal A, Lee MS, Ernst E.(PubMed)

Healthy Food Tomato Promotes Immunomodulatory Activity Against the Onset of Colitis In Vivo

Colitis is chronic a condition associated with the inflammation of the large intestine, including the colon, caecum, and rectum.

Colitis can be classified into the microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis and Behcet's colitis(a), according to the Catholic University of the Sacred Heart.


Most common symptoms of colitis are totally depending on the types. However, the general symptoms include

* Adnominal pain and diarrhea
There is a report of a 25-year-old Iranian gentleman was admitted to hospital with severe bloody diarrhea and abdominal pain as a result of herbal-induced weight loss adverse effects. On flexible sigmoidoscopy, a continuous length of congested mucosa with multiple small ulcers was seen extending up to the mid-transverse colon, in keeping with ulcerative colitis, according to the study by
Homerton University Hospital NHS Foundation Trust(1)

2. Bleeding per rectum
Acute ischaemic colitis (AIC) is being increasingly recognized as an uncommon cause of abdominal pain associated with fresh bleeding per rectum and diarrhea, according to the study by University Central Hospital(2).

3. Distention with bloody diarrhea
The typical clinical presentation is acute sudden abdominal pain and distention with bloody diarrhea(3).

4. Abdominal bloating and flatulence
In the study to estimate the prevalence of microscopic colitis and SIBO in patients with IBS, to evaluate the symptoms and the efficacy of treatment found that out of the 132 patients initially diagnosed with IBS 3% (n=4) had microscopic colitis and 43.9% (n=58) had SIBO. Diarrhea was the main symptom in patients with microscopic colitis and SIBO (p=0.041), while abdominal pain, abdominal bloating and flatulence were prominent in IBS patients (p=0.042; p=0.039; p=0.048)(4).

5. Changes in bowel habits
Abdominal pain, bloating, early satiety, and changes in bowel habits are common presenting symptoms in individuals with functional GI disorders(5).

6. Fever and severe dehydration
There is a report of a 19-year-old man with a 1-year history of ulcerative colitis presented with fever, bloody diarrhea, and severe dehydration. He was on po.48 mg methylprednisolone and 3 g mesalazine daily and has recently finished taking clarithromycin for Campylobacter jejuni infection(6).

7. Urgency
The study to examine the differing perspectives and perceptual gaps relating to ulcerative colitis (UC) symptoms and their management between patients and healthcare professionals (HCPs), indicated that fifty-five percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life over the same period. Patients ranked urgency and pain as the most bothersome symptoms(7)

8. Other symptoms
There is a report of a case of a 51-year-old Caucasian male who was evaluated for abdominal pain, elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea as a result of granulomatous enterocolitis. due to Sarcoidosis(8). Other study conducted by Anhui University of Traditional Chinese Medicine, with rats in the model group, showed lethargy, poor appetite, loss of energy, diarrhea and bloody stool(9).

If you have experienced some of the aforementioned symptoms persistently with no signs of stopping, please make sure you check with your doctor to rule out the possibility of colitis.


Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

On finding healthy foods for the treatment of colitis, researchers examined the impact of tomato lycopene extract (TLE) on intestinal inflammation.

The study included mice lipopolysaccharide (LPS)-induced innate signaling and experimental colitis fed a diet containing 0.5 and 2% TLE or isoflavone free control (AIN-76).

According to the tested assays, TLE blocked LPS-induced IkappaBalpha degradation and RelA translocation associated with the onset of colitis by blocking the inhibition of the protein involved in cytokine production.


Futhermore, MIP-2, a small cytokine mRNA accumulation in IEC-18 cells and pro-inflammatory cytokine Interleukin 12 (IL-12) induced by LPS were inhibited by the injection of TLE.


Moreover, application of TLE also increased the expression of anti-inflammatory cytokines IL-6, TNF-alpha, a regulator of inflammation and MCP-1 mRNA associated with macrophage recruitment in the colon of TLE-fed subjects.


The results strongly suggested that tomato extract inhibited the colitis in mice through its modulatory of immune and inflammatory activity.


Taken altogether, tomato may be considered a dietary supplements for the prevention and treatment of colitis, pending to large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice by Joo YE1, Karrasch T, Mühlbauer M, Allard B, Narula A, Herfarth HH, Jobin C. (PubMed)
(2) Colitis - Types and Symptoms by Kyle J. Norton

Sunday, July 28, 2019

Yoga In Regulation of Gene Expression of Related Diseases



Yoga intervention may have a potential effect in regulated gene expression in some related diseases, researchers at the University of Oslo suggested.

Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators and noncoding RNAs
3. Gene mutation is a natural process to protect the existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.

Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environmental toxins, the long term used of single or multi ingredients medication,... may also induce genetic change to the negative ways.

Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to investigate whether the effects on the mind-body system in increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effect in gene expression profiling in circulating immune cells, particularly in the molecular level.

Indeed, yoga can improve immunity through a sequence of the post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as regulators of gene expression in the innate and adaptive cell of the immune system, through noncoding RNAs, thus reducing risk of inflammatory and autoimmune diseases.

In further exploration of the yoga effect in gene expression in the molecular level, researchers at the joint study led by the Coventry University postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.

Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce implication of stress in increased production of inflammatory cytokines in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF alpha), thus reducing risk of inflammatory diseases.

And after examined the changes in gene expression that occur after MBIs and to explore how these molecular changes are related to health, through searching the database of published literature from PubMed throughout September 2016, researcher indicated that overall studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.

Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.

Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people practiced either a comprehensive yoga program or a control regimen, researchers found that SK&P program has a more rapid and significantly greater effect on gene expression in PBMCs compared with the control regimen.

Peripheral blood mononuclear cell (PBMC) include lymphocytes (T cells, B cells, NK cells) , monocytes and granulocytes which play an important role in improved immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injuring, .....

Truly, the impact of yoga in the protection of gene expression of the immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokines

Taking all together, Yoga intervention and related practices may have a profound effect on gene expression alterations through a complex network of simple gene regulation in the immune system.


For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)

Fermented Cucumber, the Natural probiotics With No Side Effects

Probiotics are good bacteria that not only balance the ratio of gut microbiota in the intestine but also react with other body systems to provide optimal health in the human.

Most common types of probiotics are lactobacilli (like Lactobacillus acidophilus and Lactobacillus GG), bifidobacteria (like Bifidobacterium bifidus) and some yeasts (like Saccharomyces boulardii).

Although all probiotics shared the same functions to improve the gastrointestinal microbiome community, different probiotics have different effects.

Most common probiotic foods are
* Yogurt, a dairy product made by fermenting milk is one of the best sources of probiotics. Epidemiologically, yogurt not only provides protein and calcium for the body but also enhance healthy gut bacteria.

Additionally, the fermented products also protect against osteoporosis, irritable bowel disease, and aids digestion.

* Kefir.
Kefir is a fermented probiotic milk drink made from kefir grains Kefir or kephir similar to those of thin yogurt.

According to the article by By Megan Ware RDN LD, Kefir as probiotic has been found to process a number of health benefits, including lowering blood pressure, cholesterol, and glucose, improved lactose tolerance, and stomach health, weight control and promoted wound healing.


More precisely,
* In immunity, probiotics stimulate the immune function against inflammatory immune disorders.

* In the digestive system, probiotics protect the gut against gastrointestinal diseases and non-gastrointestinal diseases.caused by overexpression of bad bacteria.

* In metabolism, probiotics influence the nutrient extraction from the diet, thus reducing the risk of obesity and obese complication.

* Neurologically, probiotics control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.

The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.

With an aim to find a natural compound with probiotic potential, researchers investigated 3 bacterial strains designated as 437F, 1630F and 1020G were isolated from a traditional pickle.

According to the tested results, all strains showed high acid and bile tolerance and exhibited antagonistic activity against various pathogens.


The straits also demonstrated the antioxidant activity, auto- and co-aggregation ability on the surface hydrophobicity and attachment capacity in the range of other well-known probiotic strains without inducing toxicity.

Dr.Talebi S, the lead scientist wrote at the end of the experiment, "With respect to their characteristics and safety aspect, these Bacillus species may have potential to consider as probiotics for animal and/or human applications".

Additional differentiation of the effect of fermented cucumber activity as probiotics, researchers examined a total of 38 strains which were isolated from the pickled samples.


According to the tested assays, all strain showed a significant resistance after incubation at pH 2.5 did not change markedly, above 90 % (10(9) CFU/mL) survival rate was observed.


More precisely, the strains also exhibited a high survival rate at pH 3.5 (>90 %), compared to all dead at pH 1.5 except four strains that could survive 90 min.

In bile salt solution incubation, at 0.2 %, the survival rates were 81-94 % after 24 h, compared to 59-94 % in 2 and 4 %.

Similar to the aforementioned study, the tested strains also exerted the auto- and co-aggregation ability on the surface hydrophobicity and attachment capacity.

Only four of tested strains were excluded due to safety precautions, according to antibiotic resistance patterns and certain metabolic activities.


In other words, most tested strains isolated from the fermented cucumber process the ability to improve the ratio of microbiota composition in the gut.

Taken altogether, fermented cucumber may be used as probiotics to improve the human digestive health, pending to the confirmation of the larger sample size and multicenter human study.

Intake of CuB in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(2) In vitro screening of selected probiotic properties of Lactobacillus strains isolated from traditional fermented cabbage and cucumber by Zielińska D1, Rzepkowska A, Radawska A, Zieliński K. (PubMed)
(3) Seven benefits of kefir By Megan Ware RDN LD. (Medical News Today)

Saturday, July 27, 2019

Yoga in Enhanced Immune Function

Yoga practicing may have a profound effect in improved immune function against foreign invasion, particularly in age-related immune suppression in elderly individuals

Immune function is a natural reaction of the immune system in protecting our body against foreign substances, cells, and tissues through the proper expression of the immune response.

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to evaluate the effect of yoga on mucosal immune function and mental stress with saliva samples collected from 23 adult women (age: 60.4 ± 10.4 years) before and after 90 minutes of yoga stretching or rest researchers, found that
1. Yoga group expressed a significant higher immunoglobulin A (SIgA)(a subclass of Immunoglobulin A (IgA) plays an important role in the immune function of mucous membranes)
concentration and secretion rate after yoga than before and in compared to control
2. The levels of cortisol( higher levels cortisol caused by stress has a negative effect on the immune system) concentration and secretion rate were lower and testosterone(which plays an important role in immune function in reduced risk of autoimmune disease) secretion rate higher after yoga.

After further analysis and taking into account other co-founders, researchers said, " Yoga stretching can reduce stress and enhance mucosal immune function in elderly women."

Mucosal immune function is the first line of defense of the immune system against antigens and infection and in regulated immune overreaction from unharmful sources.

According to general belief, yoga twist, compress and standing posts exercise play an important role in ameliorated alterations in the number of immune cells and cytokine dysregulation through lowering stress hormones production.

Additionally, the exercises also found to improve energy and energy balancing in the body which are necessary for the immune system to function properly.

In the concerns of yoga expression in enhanced immune system through numbers of mechanism, researchers at the Daejeon University conducted a study in healthy adults, to highlight the beneficial effects of yoga practice on bio-parameters related to immune expression found that1. Yoga group expressed significantly reduced levels of relative oxygen species(ROS), including include peroxides, superoxide, hydroxyl radical, and singlet oxygen through regulating cellular metabolism in production of ROS which have been found to have a direct influence on T cells activation, apoptosis, and immune hyporesponsiveness.

2. Yoga group demonstrated an improvement of immunity in increased levels of antioxidant in compared to control, through the effects of free radical scavengers in reduced cellular damage caused by overexpression of ROS in inducing inflammation.

3. Yoga practice also significantly increased immune-related cytokines, such as interleukin-12, and interferon-γ,....which play an important role in reduced risk of inflammatory and autoimmune diseases, including diabetes, atherosclerosis, rheumatic arthritis, and cancer.

4. The levels of plasma levels of adrenalin were reduced and serotonin was increased in a yoga group in compared with the control group.

Elevation of plasma levels of adrenalin caused by stress may suppress the immune system and increased levels of serotonin showed an opposite effect in increased killing ability of natural killer (NK) cells.
After taking into account of other co-founders, Dr. Lim SA, the led researcher said, "Regular yoga practice remarkably attenuated oxidative stress (caused by an imbalance of between the production of free radicals and antioxidants) and improved antioxidant levels of the body. Moreover, yoga beneficially affected stress hormone releases as well as partially improved immune function."
More importantly, in the review on the effects of yoga poses on psychological conditions including anxiety and depression, on pain syndromes, cardiovascular, autoimmune and immune conditions and on pregnancy.

 Dr. Field T, at the University of Miami School of Medicine, opinionated that yoga intervention induced the less production of cortisol, the hormone has a negative effect on the immune system due to stress may indeed have a profound effect in enhanced immune cellular function, particularly in psychological conditions in regulating the autoimmune and immune conditions.


Taking all together, There is no doubt that yoga practice may have a therapeutic effect in improved immune function against foreign substances, cells, and tissues through numbers of a mechanism involving different pathways.


For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Yoga stretching for improving salivary immune function and mental stress in middle-aged and older adults by Eda N1, Ito H2, Shimizu K3, Suzuki S4, Lee E4, Akama T1.(PubMed)
(2) Regular Yoga Practice Improves Antioxidant Status, Immune Function, and Stress Hormone Releases in Young Healthy People: A Randomized, Double-Blind, Controlled Pilot Study by Lim SA1, Cheong KJ1.(PubMed)
(3) Yoga clinical research review by Field T1.(PubMed)

Phytochemical Carotenoids Blocks the Liver cancer Onset and Progression

Liver cancer is a medical condition casued by irregular cell growth in the liver tissue due to the alternation of the cells DNA.

The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.


Since the organ is a soft tissue with less nerve, most liver cancer patients are diagnosed in the later stage of cancer.

liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide.
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.

According to the statistic, approximately 42,030 adults (29,480 men and 12,550 women) in the United States will be diagnosed with primary liver cancer in 2019 in the US.

Believe it or not, since 1980, the incidence of liver cancer has tripled. Between 2006 and 2015, the number of people diagnosed with the disease increased by approximately 3% annually.


The exact causes of liver cancer are not identified. However, epidemiologically, age, gender, geography, cirrhosis (severe scarring in the liver) and medical conditions such as diabetes and obesity are some of the most common prevalent factor associated with liver cancer developing.

Some researchers suggested the increased liver cancer incidence may be associated with the promotion of a high-fat diet over the past few decades.

Dr. VanSaun MN, the lead scientist wrote, "Chronic changes induced by the prolonged consumption of a high-fat diet alone culminate in the development of primary liver dysplasias".


And, "High fat diet-induced steatosis, coupled with a splenic injection model of experimental liver metastasis using syngeneic MC38 colon cancer cells, resulted in an increased number of secondary tumor nodules and metastatic burden in steatotic livers. Metastatic nodules were associated with focal peritumoral areas of infiltrating inflammatory cells and associated apoptotic cell populations".

Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.

On finding a potential ingredient for the treatment of liver cancer researchers examined the carotenoids effects on hepatocellular carcinoma (HCC) progression.


According to the tested results of the delivery of siFOXC1 using novel carotenoid functionalized dendritic nanoparticles (CDN), the CDN not only displayed a markedly reduced toxicity profile but also achieved ∼90% FOXC1 knockdown.

In other words, the established delivery CDN inhibited the expression of transcription factor FOXC1 which has been found to induce hepatocellular carcinoma (HCC) progression.


Including carotenoids, the CDN achieve the ∼18% greater delivery efficiency compared to treatments of particles with no carotenoid tagging.


Researchers after taking other factors into account said, "thereby emphasizing the role of carotenoid mediated cell internalization in the efficient delivery of CDN-siFOXC1 complex in liver cancer cells".


More precisely, using the aforementioned delivery system, carotenoids are more effective in the inhibition of liver cancer compared to oral injection.


Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of liver cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of carotenoids in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Carotenoid Nanovector for Efficient Therapeutic Gene Knockdown of Transcription Factor FOXC1 in Liver Cancer by Misra SK1, Ray T2, Ostadhossein F1, Kim B2, Ray PS2, Pan D. (PubMed)
(2) High fat diet-induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model by VanSaun MN1, Lee IK, Washington MK, Matrisian L, Gorden DL. (PubMed)

Friday, July 26, 2019

Yoga, The Best in Reduced Symptoms and Treatment of Gastroesophageal Reflux Disease

Gastroesophageal reflux disease, or GERD, is a condition of digestive disorder affecting the lower esophageal sphincter (LES), the ring of muscle between the esophagus and stomach with symptoms of heartburn or acid indigestion.

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to compared the efficacy of yoga intervention and frequent consumption of over-the-counter or prescribed proton pump inhibitors (PPI), researchers filed the following results
1. PPIs and other over counter medicine are insufficient to relieve the symptoms of gastric reflux.
The combination of yoga intervention and medicine expressed a significant reduction of the severe symptoms of GERD, including bloody stools or bloody vomiting, dysphagia in the ameliorated sensation of food being stuck in your throat. and prevented nausea.

2. The combined treatment also showed a strong effect in avoid or delay the necessity of invasive procedures

Proton pump inhibitors are a class of drugs used in conventional medicine in reduced gastric acid production with pronounced and long-lasting effects


Based on the finding information, Dr.Kaswala D, the led author said, " regular practice of Kapalbhati and Agnisar kriya along with PPI, patients with hiatal hernia had an improvement in severe symptoms of GERD, which were initially refractory to PPI alone".

Kapalbhati and Agnisar kriya, are exercises in yoga lessons with an aim to in increased digestive system and metabolism.
Hiatal hernia is an abnormality of the stomach in induced acid backs up into the esophagus, causing acid reflux or gastroesophageal reflux (GERD). In most cases, surgery is necessary, if patients do not a response to heartburn and acid reflux.medication.


Additionally, in a case study of a 14-y-old girl who had two surgeries for gastro-esophageal reflux disease (GERD) and continued with chest and abdominal pain, as well as vomiting, difficulty eating, weight loss, and anxiety assigned to 4 months of Iyengar yoga, researchers at the University of California after taking into account of her symptoms which had not been improved with treatments by specialists over an extended period of time, found that

1. Yoga intervention expressed a significant improvement of the chest and abdominal pain, and vomiting, difficulty eating, weight loss, and anxiety.
2. Yoga participated in improved school attendance, sleep, socialize, or eat, and physical functioning
3. After 4-mo treatment of Iyengar yoga, patient have resumed activities and re-engage with her environment

Iyengar, a form of Hatha Yoga emphasized on detail, precision, and alignment in the performance of posture (asana) and breath control (pranayama), according to some yoga instructors, the practice has a pronounced effect in the reduced system of digestive disorder and promoted energy restoring.
Dr. Evans S., the led author said, "(The purpose of this report is) to stimulate the scientific study of this form of treatment for children and adolescents with chronic pain".

There was a report that Iyengar yoga restorative poses with gentle strength-building poses have slowly increased symptoms of GERD of an adolescent girl.

Mrs. Beth Sternlieb, a yoga instructor at the UCLA Pediatric Pain Clinics suggested that Iyengar yoga lessons implication not only reduced intake of medication but also improved her medical complications after medication withdrawal.

Taking all together, there is no doubt that yoga may be used as an integrated form of physical exercise in reduced symptoms and treatment of gastroesophageal reflux disease.

For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Can yoga be used to treat gastroesophageal reflux disease? by Kaswala D1, Shah S, Mishra A, Patel H, Patel N, Sangwan P, Chodos A, Brelvi Z.(PubMed)
(2) Iyengar yoga and the use of props for pediatric chronic pain: a case study by Evans S1, Sternlieb B, Zeltzer L, Tsao J.(PubMed)
(3) IYENGAR YOGA INSTITUTE OF SAN FRANCISCO

Tomato Inhibits the Onset of Non-alcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH), is a type of inflammatory non-alcoholic fatty liver disease caused by a buildup of fat in the liver.

Most cases of NASH if untreated can lead to liver scars or building up of scar over time, a condition of liver cirrhosis and one of the most common causes of liver cancer.


Most people with non-inflammatory-alcoholic fatty liver disease are asymptomatic, however, the inflammation caused by non-alcoholic steatohepatitis may induce liver damage, leading to a reduced function of the liver that orchestrates the onset of liver symptoms.

Most common symptoms are abdominal swelling, enlarged blood vessels just beneath the skin's surface, enlarged spleen, red palms, and jaundice.

If you have experienced some of the aforementioned symptoms that do not recede in a short period of time, you may have some forms of liver disease. Please check with your doctor to rule out the possibility.

Out of many prevalent factors associated with increased risk of non-alcoholic steatohepatitis, some researchers suggested the rise of the condition in the US population may be correlated to the promotion of the Western diet over the past few decades.

Dr. H. Cortez-Pinto, the lead scientist said, " Comparison of their diet history with control data (C) revealed that carbohydrate consumption was lower in patients (P): P—243.6±5.7g vs. C—261.5±1.6g, P<0.05, and most patients had very low fiber intake. Conversely, total fat consumption was higher in patients: P—79.7±1.7g vs. 73.0±0.4, P<0.01. A significantly higher intake of n-6 fatty acids (P=0.003) and the then-6/n-3 ratio was found in patients, P<0.001".

And, "Our results suggest that the quality and combination of carbohydrates and fat intake may be more relevant than their isolated amount; an increased fat intake with an excessive amount of n-6 fatty acids can be implicated in promoting necro-inflammation, and provides further grounds for individualized dietary therapy".

Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In the urgency to discover healthy foods for the treatment of liver disease, researchers examined the effect of lycopene, a non-provitamin A carotenoid and the pigment principally responsible for the characteristic deep-red color of ripe tomato and tomato products on subjects with non-alcoholic steatohepatitis.

According to the review of the epidemiological study, tomato extract supplementation showed a significant protective effect against HFD-induced hepatic inflammation compared supplementation of lycopene.

In patients with NASH, increased levels of plasma lycopene may have a strong impact on the progression of NASH as patients have been shown to have significantly reduced plasma lycopene.

In vivo, dietary lycopene inhibits liver carcinogen-induced preneoplastic lesions in the rat liver that was effective in reducing NASH-promotion in rats.

The efficacy of lycopene in the inhibition of NASH and another chronic disease may be associated with the body in lycopene metabolism involved in both the chemical and enzymatic modifications.

Futhermore, in vivo synthesis of ACR from lycopene showed toattenuate hepatic steatosis, by decreasing the macrophage conditioned medium induced and TNFα-mediated induction of pro-inflammatory cytokine and chemokines.

Taken altogether, tomato processed a high amount of lycopene may be considered a dietary supplements for the prevention and treatment of NASH, pending to large sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention by Ip BC1, Wang XD. (PubMed)
(2) How different is the dietary pattern in non-alcoholic steatohepatitis patients? by H. Cortez-Pintoa, L. Jesusa, H. Barrosc, C. Lopesc, M.C. Mourab, and M.E. Camiloa. (Clinical Nutrition)

Thursday, July 25, 2019

Yoga, the Best in Reduced Risk and Treatment of Metabolic Syndrome

Metabolic syndrome is a condition of abnormal blood pressure, blood sugar, excess body fat around the waist,... which can lead to early onset of diabetes, cardiovascular disease,.
..
People who participated in yoga class regularly are likely to have a lower risk of metabolic syndrome development, a renowned study suggested.

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the Vanderbilt University School of Medicine, yoga, a form of physical activity that incorporates psychological components (e.g., maintaining attention, relaxation) may process health benefits in the alleviated risk of metabolic syndrome and improved mental stress and quality of life.

In a sixty-seven adults at risk for MetS enrolled (mean age [SD]: 58 [10] years; 50% male; 79% non-Hispanic White) in 12-week yoga program coupled with an evidence-based health education program (HED), in compared to HED alone, researchers found that participants in the yoga program coupled with an evidence-based health education program (HED) showed a significant improvement of twice quality of life domains in compared health education group.


Dr. Sohl SJ, the lead author said, " implemented lifestyle education along with yoga to evaluate the potential unique effects of yoga on participants at risk for MetS".

Furthermore, in another 12 weeks yoga lessons of 173 Chinese men and women aged 18 or above either assigned to either the yoga intervention group (n = 87) or the control group (n = 86), after taking into account of other confounders, researchers indicated that yoga group showed a greater decline in waist circumference (p<0.001), fasting glucose (p<0.01), triglycerides (p<0.05), and MetS z score, in comparison to control.

Also, the yoga group expressed a significant improved general health perception (p<0.01), physical component score (p<0.01), and social functioning (p<0.01) domains score of HRQo with no difference in the enhanced systolic/diastolic blood pressures or high-density lipid protein cholesterol in both groups.

Promisingly, the 2009-2012, 48-week randomized trial comparing restorative yoga vs. stretching among underactive adults with the metabolic syndrome at the Universities of California, San Francisco and San Diego of 180 participants randomized and 135 (75%) completed the trial, at 12 months, suggested that yoga participants displayed a magnificent decrease of fasting glucose, insulin, and HbA1c and an increase in HDL-cholesterol in compared to stretch group.

Taking all together, yoga may be used as physical therapy in reduced risk and treatment of metabolic syndrome with greater effect in comparison to other forms of treatment in the article, but participants should always engage only to class tailored to their needs.


For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Yoga for Risk Reduction of Metabolic Syndrome: Patient-Reported Outcomes from a Randomized Controlled Pilot Study by Sohl SJ1, Wallston KA2, Watkins K3, Birdee GS3.(PubMed)
(2) Effects of a 12-Week Hatha Yoga Intervention on Metabolic Risk and Quality of Life in Hong Kong Chinese Adults with and without Metabolic Syndrome by Lau C1, Yu R1, Woo J1.(PubMed)
(3) Restorative yoga and metabolic risk factors: the Practicing Restorative Yoga vs. Stretching for the Metabolic Syndrome (PRYSMS) randomized trial by Kanaya AM1, Araneta MR2, Pawlowsky SB3, Barrett-Connor E2, Grady D3, Vittinghoff E3, Schembri M3, Chang A3, Carrion-Petersen ML2, Coggins T3, Tanori D2, Armas JM3, Cole RJ4.(PubMed)

Phytochemical Lycopene Protects the Kidneys Against Renal/Kidney Cancer

Kidney cancer or renal cancer is primary cancer caused by irregular cell growth in the kidney tissue.

Kidneys are to bean-shaped organs located below the rib cage, one on each side of your spine with a function to filter out blood and remove waste through urinary secretion.

The kidney also plays a critical in maintaining the levels of fluids in the body, by removing extra fluids to make urine.

Furthermore, the kidney also regulates electrolytes, blood pressure, maintains acid-base balance, produces hormone calcitriol, renin, and erythropoietin.

There are 2 most common types of kidney cancer including
* Renal cell carcinoma is the most common type of adult kidney cancer, originated in the lining of the proximal convoluted tubule that transport primary urine, accounting for over 85% of all kidney cancer diagnosed.

* Urothelial carcinoma is also called transitional cell carcinoma accounting for 10% to 15% of the kidney cancers diagnosed in adults.

The stages of renal cell carcinoma are
1. Stage 0
Kidney (renal cells) cancer is classified as Stage 0 if the cancerous cell has not penetrated in deeper tissue but in the surface of the kidney lining.
2. Stage I
In stage I, The cancerous cells are no longer in the surface but have invaded into deep kidney lining, but still completely inside the kidney.
a. Stage IA1
The cancer is not ≤ 3 mm (1/8 inch) deep and ≤ 7 mm (1/4 inch) wide.
a.1. Stage IA1: The spreading is < 3mm(1/8 inch) deep and & less than 7mm (1/4 inch) wide.
a.2. Stage IA2: The invasion area is ≥ 3 mm but ≤ 5 mm (about 1/5 inch) deep and & less than 7 mm (about 1/4 inch) wide.
b. Stage IB: cancer in this stage have invaded the connective tissue, & less than 5mm (1/5 inch).
b.1. Stage IB1: Cancer is 4 cm large (1 3/4 inches).
b.2. Stage IB2: Cancer is ≥ 4 cm (1 3/4 inches) but & less than 5cm (1/5 inch)
3. Stage II
In stage II, the cancerous cells have spread to distant tissues but are still within the kidney.
4. Stage III
In this stage, cancerous cells have spread to the tissues immediately surrounding the kidney.
5. Stage IV
In the stage, IV is the most advanced stage of renal cell carcinoma as cancerous cells have spread to the distant parts of the body

Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

With an aim to find a potential compound for the treatment of kidney cancer, researchers examined the role of a lycopene-rich diet in the development of RCC in the TSC2 mutant Eker rat model.

Selected 10-week old female Eker rats (n=90) in the study were assigned in equal numbers to receive 0, 100 or 200mg/kg of lycopene as part of their daily diet sacrificed at the 18 months.

According to the tested assays, tumor size was decreased from 94% in control animals to 65% in the lycopene group.

Furthermore, the mean numbers of renal carcinomas and tumor length were statistically significantly decreased in the lycopene group compared to untreated controls. More precisely, tumor numbers decreased (P<0.002) in the lycopene group were linearly (P<0.003) to the increased lycopene injection from 0 to 200.

Compared to lycopene treated group, the control rats fed only the basal diet had a greater length of tumors.

Additional differentiation of lycopene efficacy, researchers found that lycopene inhibited the kidney cancer cell by blocking the protein in signaling cell proliferation, and in promoting the cancer cell invasive response.

Based on the findings, researchers wrote, "dietary supplementation with lycopene attenuates the development of renal cell cancers in the predisposed TSC2 mutant Eker rat model".

Taken altogether, lycopene may be considered supplements for the prevention and treatment of kidney cancer, pending on the confirmation of the larger sample size and multicenter human study.

Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model by Sahin K1, Cross B2, Sahin N1, Ciccone K2, Suleiman S2, Osunkoya AO2, Master V2, Harris W2, Carthon B2, Mohammad R3, Bilir B2, Wertz K4, Moreno CS2, Walker CL5, Kucuk O. (PubMed)
(2) A tomato lycopene complex protects the kidney from cisplatin-induced injury via affecting oxidative stress as well as Bax, Bcl-2, and HSPs expression by Dogukan A1, Tuzcu M, Agca CA, Gencoglu H, Sahin N, Onderci M, Ozercan IH, Ilhan N, Kucuk O, Sahin K. (PubMed)
(3) Most common Types of Cancer -Kidney Cancer (Renal Cell Carcinoma) by Kyle J. Norton

Wednesday, July 24, 2019

Yoga Intervention in Enhanced Smoking Cessation

Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the joint study led by the Alpert Medical School of Brown University in examine the smoking-relevant characteristics of individuals enrolling in an 8-week randomized controlled trial, for testing yoga as a complementary treatment to standard smoking cessation, on the sample of 55% female, 86% non-Hispanic white, with a mean age of 46 years,
1. Males smoked more cigarettes/ day than females and had the lower motivation to quit smoking
2. Females were more likely to smoke for weight control, social and mood-related reasons, and had higher expectations for the efficacy of yoga
3. Age was negatively associated with the presence of other smokers in the household, and smoking in response to negative moods
4. And Age was associated with more willing in quitting

After taking into account for other co-founders, researchers said, "both males and females were interested in a program offering yoga as a complementary therapy for smoking cessation".

The results indicated that yoga may be considered as an integrated form of exercise to assist smoking.cessation.

Further discussion of smoking cessation, in a study to examine the rates of cessation among women randomized to either a novel, 8-week Yoga plus Cognitive Behavioral Therapy (CBT) smoking cessation intervention versus a Wellness program plus the same CBT smoking cessation intervention, scientists showed that after 8 weeks period
1. Innovative treatments are needed to address barriers as mentioned in the above study for successful smoking cessation among men and women.
2. Yoga may be an effective complementary treatment for smoking cessation
3. Yoga can offer an alternative to traditional exercise for reducing negative symptoms that often accompany to smoking cessation and predict relapse to smoking among recent quitters.


The results of finding suggested that Yoga plus Cognitive Behavioral Therapy (CBT) are the better choices to improve smoking cessation outcome, compared to yoga alone or standard treatments.


Additional analysis of the effect of yoga intervention in smoking cessation, researchers at the University of Cincinnati, conducted a review of literature published of database from MEDLINE (PubMed), EBSCOHOST, PROQUEST, MEDINDIA, CINAHL, Alt HealthWatch, and AMED between 2004 and 2013, suggested that 10 studies satisfied the criteria and guidelines selected have produced the following results
1. Yoga participation expressed a significant effect in improved quitting smoking rates in the majority of studies
2. Yoga-based interventions hold a promise for smoking cessation

Unfortunately, all these studies also expressed some of the limitations including short follow-up measurements and short duration of intervention, Dr. Dai CL, the led author concerned


The finding evidence suggested that yoga adapted to smoker age, gender,...... and used in conjunction with standard treatment may have a profound effect in enhanced smoking cessation in short-term.


For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Who Enrolls in a Quit Smoking Program with Yoga Therapy?by Bock BC1, Thind H2, Dunsiger S3, Fava JL4, Jennings E5, Becker BM6, Marcus BH7, Rosen RK3, Sillice MA8.(PubMed)
(2) Yoga as a complementary treatment for smoking cessation: rationale, study design and participant characteristics of the Quitting-in-Balance study by Bock BC1, Morrow KM, Becker BM, Williams DM, Tremont G, Gaskins RB, Jennings E, Fava J, Marcus BH (PubMed)
(3) Between inhale and exhale: yoga as an intervention in smoking cessation by Dai CL1, Sharma M.(PubMed)

Herbal Bilberry Normalizes the Angiogenesis In the Body

Angiogenesis refers to the formation of new blood vessels from the existing vasculature.

Angiogenesis, on one hand, plays a critical role in repairing the tissue damages including arteriosclerosis, myocardial infarction. On another hand, the expression of angiogenesis has been found to cause diseases and induce progression of retinopathies, benign tumor, and cancer.

In other words, abnormal blood vessel growth that cause either excessive or insufficient has been linked to underlying many deadly and debilitating conditions.

Under normal condition, the development of angiogenesis totally depends on the functional demands of the body. For example, exercise stimulates angiogenesis in skeletal muscle and heart and a lack of exercise can lead to capillary regression.

Clearly, these results demonstrated the needs of angiogenesis for the body to function better and the formation of new blood vessels occurs throughout human life.

However, in the cancer perspective, new blood vessel growth is important for cancer proliferation and metastatic spread. The survival of tumor cells totally depends on an adequate supply of oxygen and nutrients.

Dr. the lead scientist said, "Levels of expression of angiogenic factors reflect the aggressiveness of tumor cells. The discovery of angiogenic inhibitors should help to reduce both morbidity and mortality from carcinomas".

In other words, if we can stop the tumor in stimulating the production of new blood vessels to supply energy for them to grow, we may cure cancer.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

With an aim to find potential treatment for diseases associated with angiogenesis,with no side effects, researchers examined the antiangiogenic properties and antioxidant activities (a) of the main anthocyanidins (delphinidin, cyanidin, and malvidin) found as constituents in Vaccinium myrtillus (bilberry) anthocyanosides (VMA) and (b) of N-acetyl-L-cysteine (NAC).

Anthocyanidins exerted a significant inhibition of vascular endothelial growth factor (VEGF) associated with the grow od new blood vessel in a concentration-dependent manner.

Anthocyanidin at 3 and/or 10 microM are the most effective compared to those of NAC at 1 microM (the only concentration tested).
Moreover, both anthocyanidin (0.3-10 microM) and NAC (1-1000 microM) concentration-dependently also exerted a significantly scavenged the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.

The findings suggested that VMA processes an anti-angiogenic activity depending on the main constituent anthocyanidins (delphinidin, cyanidin, and malvidin), presumably via antioxidant effects.

Additionally, in vitro and in vivo, Vaccinium myrtillus (Bilberry) extracts (VME) showed an anti-angiogenic effect on 0.3-30 µg ml(-1)) compared to those of GM6001 (0.1-100 µM; a matrix metalloproteinase inhibitor).

In human umbilical vein endothelial cells (HUVECs), VME inhibited VEGF-A-induced proliferation of HUVECs.

According to the vivo assay, intravitreal administration of VME inhibited the formation of neovascular tufts during oxygen-induced retinopathy in mice.

The results suggested that VME may be effective against retinal diseases involving angiogenesis.

Taken altogether, bilberry may be considered a functional remedy for the prevention and treatment of diseases involved angiogenesis, pending to the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Inhibitory actions of bilberry anthocyanidins on angiogenesis by Matsunaga N1, Tsuruma K, Shimazawa M, Yokota S, Hara H. (PubMed)
(2) Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In Vivo by Matsunaga N1, Chikaraishi Y, Shimazawa M, Yokota S, Hara H. (PubMed)
(3) Angiogenesis in Cancer by Naoyo Nishida,1,2 Hirohisa Yano,1 Takashi Nishida,3 Toshiharu Kamura,2 andMasamichi Kojiro. (PMC)