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Thursday, October 10, 2019

Honey, the Potential Chemo Replacement for the Treatment Cancers, Scientists Say

Honey may process certain chemical compounds which have a potential effect in the reducing risk and treatment of cancers with no side effects, some scientists suggested.

Cancer cells are the type of cells which can grow indefinitely compared to normal cycle which can only survive after certain cycle division.

According to cellular biology, in a fully grown adult cell, the rate of cell proliferation is much less, and under normal circumstances and cell division in an adult can only occur when there is the need to replace cells that have been lost, damaged, or worn out.

Most cancers start in the cells on the surface of the inner lining of the tissue of the specific organ.

At the early stage, most cancer tumors do not induce any symptoms. However, after colonizing most tissue, the disorderly proliferative tumor can suppress the nearby tissue including nerve cells and blood vessel, causing localized pain and severe symptoms depending on the types of cancer.

Also, at this stage, malignant cells can also travel through lymph and blood to infect other healthy tissue, a distance away from the original site.

Although there are many risk factor associated with the onset of cancer, people with a genetic preposition are at highest risk.

Men who carry genetic mutation BRCA1, BRCA2, and HOXB13, inherited from the parents are at 70% risk of the prostate cancer, and women who carry the mutated genes BRCA1 and 2 have an increased risk breast cancer of over 55%.

Sadly, more than 12 percent of men with prostate cancer tested positive for hereditary mutations of cancer-causing genes, 87% of women reported BRCA testing by one-year post-diagnosis of breast cancer.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

With an aim to find a natural ingredient for the prevention and treatment of cancer with no side effects, a joint study led by the Universiti Sains Malaysia was conducted to examine the role of honey in modulating the development and progression of tumors or cancers.

By searching the available data online literature, researchers found that there is available evidence (some of which is very recent) with regards to the antimetastatic, antiproliferative and anticancer effects of honey in various forms of cancer.

Honey was highly cytotoxic against tumor or cancer cells, while it was non-cytotoxic to normal cells.

Honey inhibited growth and proliferation of tumors or cancers.

Application of honey inhibited carcinogenesis by modulating the molecular processes of initiation, promotion, and progression stages.

Furthermore, in the study to examine the honey and royal jelly effects against cisplatin-induced nephrotoxicity in patients with cancer, researchers examined the results of patients with cancer assigned for cisplatin chemotherapy randomly divided into bee honey and royal jelly groups pretreated before the initiation and during cisplatin chemotherapeutic regimen and control group on cisplatin only and showed that

* Patients on crude bee honey and royal jelly capsules showed lower serum levels of renal injury products (creatinine and urea) compared to those in the control group.
* The changes in kidney parameters were significantly (p < 0.05) lower when compared within the bee honey group before and after cisplatin treatment.

These results indicated bee honey and royal jelly as natural compounds are effective in reducing cisplatin nephrotoxicity and may offer a promising chance for clinically meaningful prevention with no side effects.

Interestingly,  the lead author in the examine the overwhelming evidence of the role of diet and lifestyle in cancer risk and prevention, suggested that there is a growing interest into the search for chemopreventative or chemotherapeutic agents derived from natural products.

And, honey is an important source of bioactive compounds derived from plants and recent years have been under the intensified study for its anticancer properties.

Recently, the role of honey in targeting key hallmarks of carcinogenesis, including uncontrolled proliferation, apoptosis evasion, angiogenesis, growth factor signaling, invasion, and inflammation has been presented. in numbers of conventional research.

Taken altogether, honey may be used as a functional food for the prevention of cancers and a secondary therapy combined with conventional medicine for the treatment of cancers.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.










Sources

(1) Effects of honey and its mechanisms of action on the development and progression of cancer by Erejuwa OO1, Sulaiman SA2, Wahab MS. (PubMed)

(2) Effect of Honey and Royal Jelly against Cisplatin-Induced Nephrotoxicity in Patients with Cancer by Osama H1, Abdullah A1, Gamal B1, Emad D1, Sayed D1, Hussein E1, Mahfouz E1, Tharwat J1, Sayed S1, Medhat S1, Bahaa T1, Abdelrahim MEA. (PubMed)

(3) Honey and Cancer: Current Status and Future Directions by Porcza LM1, Simms C2, Chopra M. (PubMed)

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