Green bean, the Anti-Hyperglycemic Remedy

Hyperglycemia is a condition of abnormally high blood sugar in the bloodstream, inducing diabetic complications in patients with type 2 diabetes.

In order words, hyperglycemia is a result of the body which does not properly use or make the hormone insulin.

The condition is also considered a hallmark of patients with type 2 diabetes. Another hallmark is insulin resistance.

Hyperglycemia occurs mostly due to poor control and management in patients with diabetes such as
a poor diet, physical inactivity choices, symptoms of medicines intake.

Some patients with diabetes also experience symptoms of hyperglycemia due to skipping or not taking enough glucose-lowering medication.

Most common symptoms of hyperglycemia are frequent urination, increased thirst, blurred vision, persistent fatigue, and headache.

According to the epidemiological studies, untreated or long term persistently hyperglycemia in patients with diabetes has been found to induce serious symptoms such as shortness of breath, and confusion.

In serious cases, untreated hyperglycemia also induces long-term complications of cardiovascular disease, nerve damage associated with skin infections, and ulcerations.

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 difference species, belonging to the family Fabaceae and native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. The veggie can be classified into two major groups, bush beans, and pole beans.

On finding a potent veggie for the prevention of hyperglycemia, researchers examiend the effects of bean extract on overexpression of free radicals and higher reactive oxidative species (ROS) production induced high blood glucose.

The randomized controlled trial (RCT) study included mice (Micetus norvegicus) of Wistar strains randomized in five groups: P1-negative control, positive P2-control, P-3 ethanol extract group of 200mg / kg BW, P4-group 400mg / kg BW, P5- group 600 mg / kg BW.

According to the differences in blood sugar levels and superoxide enzyme levels of intergroup dismutase, ethanol extract of green beans 600 mg/kg BW from day 14 to day 28 (p <0.05) showed a statistically significant decrease in blood glucose levels.

However, ethanol extract of green beans 200 mg/kg BW and 400 mg / kg GB from day 7 until day 28 (p> 0.05) did not have any effect on the decreasing blood glucose in the tested rats.

The tested ethanol extract of green beans showed no effect on the levels of activity of the superoxide dismutase enzyme (p = 0.830).

In other words, green bean extract inhibited the expression of hyperglycemia without affecting the levels of antioxidant enzymes produced by the host at a dose depending manner.

Based on the findings, researchers said, "Giving ethanol extract of green beans 600 mg/kg BW effectively decrease blood sugar in male Wistar mice (Micetus norvegicus) from day 14 to day 28".


Taken altogether, green beans may be used as an adjunct therapy for the prevention of diabetes by inhibiting the expression of hyperglycemia, pending to the confirmation of larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Bean Ethanol Extract (Phaseolus Vulgaris L.) on Superoxide Dismutase Activity in Wistar Mice (Micetus Norvegicus) Hyperglycemia by Ade Putra Fratama Sinaga1), Syafruddin Ilyas2), Dwi Rita Anggraini.